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Background, Interest,
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| | Ratio Flux LLC | Max Green | Founder & Managing Partner |
Small Business
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Office of Technology Transitions (OTT)
| | Ratio Flux was founded on one core mission: Accelerate Human Innovation. We operate at the intersection of science, markets, and capital — helping founders, investors, researchers, and companies convert uncertainty into investable insights.
We facilitate a creative application of the scientific method to your business, prioritizing curiosity, discipline and intellectual honesty to help innovators de-risk innovations and build a bridge between discovery, capital strategy, and execution readiness.
Our framing of the scientific method embraces the following approach:
Challenge Thoughtfully.
Experiment Consistently.
Analyze Honestly.
This shows up in everything we do…our accelerator programs, our entrepreneur pitch development, our customized discovery workshops, and our personalized coaching engagements.
We specialize in cutting through the noise to help you align resources towards viable business opportunities and create capital efficiency by focusing on what the market says is important. We challenge your assumptions and work to establish patterns about your customer’s behavior, helping you illuminate strategies that generate sales.
Our work has been shaped over the past 20 years working directly with early-stage ventures, commercialization accelerators, and founders navigating the complex path from idea to product. We have served thousands of companies, entrepreneurs & scientists through programs stretching across four continents and different cultures.
This led us to the recognition that: Innovation trends evolve -- The scientific method endures. |
| TX |
| | OmniSync Incorporated | Rupak Doshi | CEO |
Small Business
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Integrated Strategies
| | Real world data-driven commercialization enablement system as a service. |
| CA |
| | CPFD Software | Rajat Barua | CEO |
Small Business
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Cross-Cutting
| | CPFD Software is a pioneering technology company in the field of computational fluid dynamics (CFD). Building upon a unique heritage from Los Alamos National Laboratory, CPFD Software expanded fluid-flow modeling to the simulation of industrial-scale fluid-particle systems. Our flagship product, Barracuda Virtual Reactor, is a physics-based engineering software package capable of predicting fluid, particulate-solid, thermal and chemically reacting behavior. Our original product, Arena-flow, is specialty software used by the metal casting industry to simulate the production of sand cores and molds. Spanning diverse energy and energy-intensive industrial applications, companies, national labs, research institutions, and universities around the world partner with CPFD Software to solve some of their most complex engineering and technological challenges. |
| TX |
| | Essential Leap, LLC | Veronica Rocha | CEO |
Small Business
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Cross-Cutting
| AOI 2: Public/Private Partnerships | Essential Leap, LLC accelerates cleantech adoption through results-driven, end-to-end market development. We focus on building the market conditions needed for commercial adoption and growth. We work at the intersection of business, engineering, policy, and partnerships to help you:
1. Create demand by clarifying value and educating customers who are not yet ready to buy.
2. Build market readiness by developing the ecosystem, including forming partnerships and identifying enabling infrastructure required for adoption.
3. Expand commercial reach into new customer segments and geographies.
3. Navigate market structures and regulations that shape how and where your product can scale.
4. Pursue non-dilutive, catalytic funding to overcome initial financial hurdles, de-risk pilots and First-Of-A-Kind (FOAK) projects, and attract mainstream investors.
5. Turn pilots and FOAK deployments into credible commercial proof that supports repeatable sales.
Scaling cleantech requires more than strong technology. Essential Leap brings together experience across business strategy, engineering, public policy, non-dilutive funding, and project development to help companies navigate every market barrier that stands between proven solutions and widespread adoption. By integrating these disciplines, we help reduce commercial and market risk while accelerating adoption. This integrated approach allows us to move faster than siloed advisors and reduce handoffs that stall momentum. |
| HI |
| | TechScale Solutions, LLC | George Roberts | President |
Small Business
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Cross-Cutting
| Technology Prototype Scale-up and Commercialization | TechScale Solutions, an engineering consulting firm based in Groton, Connecticut, USA, specializes in guiding clients through the process of scaling up technology prototypes into commercial products. Our expertise encompasses new product development, cost modeling, manufacturing scale-up, supply chain development, and product integration for novel materials and/or components.
We offer a comprehensive suite of services encompassing the development of human capital, operational processes, technological advancements, and problem-solving capabilities necessary for the successful commercialization of novel products. Our areas of specialized expertise include fuel cells, electrolyzers, flow batteries, hydrogen purification, electrochemical purification of metals, and carbon dioxide capture and conversion.
Example client projects include:
• Hydrogen Generation: Provided technical and project management support for reduced-cost, high-performance PEM electrolyzers.
• Energy Storage: Managed a cell stack development project to scale from lab scale to a grid-scale flow battery.
• Fuel Cells: Guided international and US engineering teams to develop a PEM fuel cell stack for heavy-duty transportation.
• CO2 Capture and Conversion: Provided guidance to scale up carbon capture and electrochemical CO2 conversion technologies.
• Metal Purification: Advised engineering teams on the scale up of an electrochemical cell stack for a novel copper refining process. |
| CT |
| | Intellectual Assets / Center for Advanced Technology Solutions | David McFeeters-Krone | President |
Small Business
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Advanced Manufacturing (Industrial)
| Commercialization Acceleration | The Center for Advanced Technology Solutions (CATS) is a national program designed to help accelerate commercialization by identifying key production hurdles for manufacturers and then finding solutions to solve them.
Working in partnership with the Manufacturing Extension Partnership (MEP) National Network, CATS is a proven commercialization acceleration and business development program purpose-built to bridge the gap between manufacturers with unmet technical needs to solutions anywhere in the national innovation ecosystem.
The program's core function is identifying specific technical and commercial barriers facing manufacturers and connecting them to the right federal, academic, and industry resources to overcome those barriers. Under this TCF initiative, that capability would be deployed in a targeted way: serving the existing partners of National Laboratories — licensees, CRADA partners, and active R&D collaborators — who are working to bring lab-developed technologies to market but face real-world manufacturing hurdles that threaten to stall commercialization progress.
These partners have already cleared the hardest barrier — establishing a relationship with a National Lab. What they often lack is the manufacturing expertise, prototyping access, process guidance, or industry connections needed to scale their technology into a viable product. CATS is designed precisely for this gap. Real-world examples include connecting companies to AIM Photonics for multi-chip module prototyping, linking hard-tech ventures to NETL, routing firms to NASA and Penn State for prototype development, and directing early-stage companies toward hard-tech accelerators for scale-up support.
By embedding CATS services within the National Lab commercialization ecosystem, this program would deepen and extend existing lab-industry partnerships rather than simply creating new ones — increasing the likelihood that licensed technologies and joint R&D efforts result in tangible commercial outcomes. The program is scalable across multiple labs, sustainable beyond the period of performance, and adaptable to sector-specific priorities including critical minerals, advanced manufacturing, and energy security — all crosscutting priorities identified in this lab call.
Intellectual Assets is a principal for the program and lead for the West Coast. IA has decades of TT experience and an active member of the FLC & MEP national networks. CATS is run by the RI Research Foundation. |
| OR |
| | Sinteag Ventures, Inc. | Skip Middleton | President |
Small Business
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Strategic Programs
| Critical Infrastructure Cybersecurity, Interdomain Routing Resilience | Sinteag Ventures has developed Invariant Vector Defense (IVD), a TRL-6 network defense architecture designed to mitigate large-scale distributed attacks affecting critical infrastructure, utilities, and backbone networks.
IVD detects distributed attacks by extracting invariant statistical features from packet metadata and converting them into multidimensional behavioral signatures (Psi-vectors). These signatures allow the system to treat large multi-origin attacks as single macro-objects and generate upstream mitigation rules rather than relying on millions of IP-based filters.
The architecture includes edge telemetry sensors, regional synthesis nodes, and a policy engine capable of generating FlowSpec-compatible control-plane actions. The approach enables suppression of volumetric attacks closer to ingress points, reducing control-plane instability and bandwidth saturation in downstream infrastructure.
Sinteag is seeking collaboration with DOE national laboratories interested in evaluating routing-layer resilience for critical infrastructure networks, including energy sector communications, utility network interconnections, and multi-domain routing environments.
Potential collaboration activities include:
• multi-AS routing testbed evaluation
• upstream mitigation and FlowSpec policy validation
• control-plane stability and rule propagation studies
• resilience modeling for energy and utility communications networks |
| NC |
| | University of Texas at Arlington | Xiaoqiang Li | Assistant professor of research |
Academic
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Renewable Energy Integration (REI)
| geochemistry, rock-water interactions, element characterization | My previous study was focused on geology and geochemistry of petroleum and coal, with a strong record in natural gas geochemistry, isotope geochemistry, sedimentary geology of coal and shales. My current research include: 1) H2 production in coals and petroleum reservoirs: 2) H2 production through serpentinization in ultramafic rock; 3) rare earth element mobility in ultramafic rocks; 4) critical minerals and REE recovery in coals and ultramafic rocks. To achieve the studies on the critical mineral and REE, several techniques will be used in my lab and my host university, including SEM-EDS, TEM, Raman microscopy, ICP-MS, XRD, TGA, EMPA. These tools help to answer the questions: what type of REE and how much REE in samples; 2) where does REE elements are hosted; 3) how chemical environments will influence the element redistribution. I am looking for the collaboration on proposal on critical element recovery and geological H2 production, and my contribution is to characterize the elements in the host materials and elucidate the distribution of REE elements due to the change of environments and reactions, simulation H2 production through water rock interactions at different conditions. |
| TX |
| | OSRS Group | Michael Corsello | Research Computer Scientist / Geoinformaticist |
Small Business
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Cross-Cutting
| Geospatial Analytics and Modeling | OSRS Group is developing geospatial analytics capabilities for Global Lattices at uniform resolution (GLOBE) and geospatial risk management (GRAMI). OSRS Group performs cloud, co-location and on-premises host for technologies we develop and technologies co-developed with out partner and clients.
We are interested in partnering and co-developing technologies for the energy and utilities sectors.
OSRS Group is a collaborative research and development consultancy, with the primary goal of researching, developing and providing advanced computing capabilities. We achieve this goal through fostering collaboration between our member partners.
We are the creators and stewards the System of Systems by Design (SoSD), Systematize and EcoCAD methodologies.
We do collaborative R&D with our clients principally in:
Software:
Analytics and Algorithm Design
Big Data and Distributed Computing at Scale
Cybersecurity and Information Assurance
Geospatial and Location Based Technology
Temporal, BiTemporal, TimeSeries and Space-Time Processes
Processes and Systems Engineering:
Organizational Change Management and Planning
Operational / Business Process Modeling
Software Engineering and Needs Planning and Management
System of Systems Engineering
Principally for the government, defense, engineering and scientific communities. |
| VA |
| | Vital X LLC | Jerry Salyers | CEO |
Small Business
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Integrated Strategies
| Lab call | Organization Name: VitalX
Primary Contact:
Jerry Salyers
xacmi21@outlook.com
3047121509
Technology/Capability Area: Rare Earth Element (REE) extraction and critical minerals commercialization from metallurgical coal and associated clays, integrated with energy systems and data-driven process optimization.
Facilities / Assets:
35 million tons of metallurgical coal and REE-bearing clays, feedstock ready for retrieval (no blasting)
Underground and surface mining infrastructure
Operations aligned with environmental management obligations
Potential for pumped storage hydro and geothermal-cooled data center integration
Partnership Interest:
Seeking collaboration with DOE National Laboratories to develop and scale REE extraction, separation, and commercialization technologies. VitalX combines immediate access to feedstock, industrial expertise, and integrated energy/data capabilities to support lab-led commercialization projects under the FY26 Technology Commercialization Fund (TCF) CLIMR Lab Call.
Additional Notes:
Safe, environmentally responsible critical mineral recovery with scalable energy integration and data-enabled process optimization, designed to accelerate commercialization in collaboration with DOE labs. |
| WV |
| | Rare Innovation | Timothy Raines | Managing Partner |
Small Business
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Strategic Programs
| Commercialization | Rare Innovation is a full service science and technology commercialization provider and business development partner to labs, researchers, and small businesses. Rare Innovation has had hundreds of engagements with SBIR funded companies, is a DOE Voucher Provider for commercialization services and a NLR WPTO TEAMER Marine Energy Facility.
Rare Innovation provides self-guided programming for lab-to-market, focused mentoring support, and "done for you" startup business development for IP that needs full service startup formation and market engagement. |
| FL |
| | Cascade Biocatalysts Inc. | James Weltz | Co-Founder and CSO |
Small Business
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Advanced Manufacturing (Industrial)
| TPL-0000071 | Cascade Biocatalysts is a U.S.-based manufacturer of advanced enzyme immobilization resins and immobilized biocatalysts that enable durable, high-performance cell-free biomanufacturing. Our platform technology stabilizes enzymes through covalent immobilization within tunable polymer-brush architectures, enhancing resistance to thermal deactivation, organic solvents, and mechanical stress commonly encountered in industrial chemical processes. This stabilization enables enzymes to operate across broader temperature, solvent, and pH regimes while maintaining high turnover numbers, directly supporting process intensification and extended catalyst lifetimes in continuous or semi-continuous manufacturing environments.
Cascade’s immobilization materials are designed to improve the technoeconomic feasibility of enzymatic routes for the production of fuels, commodity and performance chemicals, and chemical intermediates from renewable feedstocks. By enabling enzymatic catalysis under industrially relevant conditions—including biphasic systems, elevated temperatures, and non-aqueous media—our technology expands the accessible design space for low-emissions manufacturing pathways that displace traditional thermochemical synthesis.
Cascade Biocatalysts is actively seeking to partner with national laboratories, academic institutions, and industrial manufacturers to deploy immobilized enzyme systems in DOE-aligned applications such as sustainable fuels and chemicals, waste-to-value processes, and electrified or hybrid biomanufacturing platforms. As a domestic supplier of immobilization materials and engineered enzyme systems, Cascade is positioned to support the development of resilient U.S. biomanufacturing infrastructure for next-generation low-carbon chemical production. |
| CO |
| | Southern Beams Builds, Inc. | Dr. Ryan Wartena | CEO |
Small Business
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Integrated Strategies
| Modular Power Units | Southern Beams Builds, Inc. (SBBI) is a U.S.-based developer of rapidly deployable solar-battery infrastructure designed to enable resilient energy and compute capabilities for commercial, research, and defense environments. Its flagship system, Dragon Wings™, integrates photovoltaic generation, energy storage, power electronics, and edge-compute readiness into a transportable 20-foot ISO container form factor. The platform is designed for rapid deployment (minutes, not weeks), silent operation, and fuel-free energy delivery, addressing growing needs for distributed power and science-AI infrastructure.
SBBI’s interest in the FY26 TCF Base CLIMR Commercialization Enabling Lab Call is to accelerate transition of advanced energy, autonomy, materials, and AI technologies from laboratory environments into field-deployable systems. Dragon Wings serves as a modular commercialization bridge — enabling national labs, universities, and industry partners to validate technologies under real-world operational constraints such as constrained energy budgets, remote deployment, and resilient communications. The company seeks collaborative opportunities to integrate emerging innovations (energy optimization, advanced sensing, digital engineering, edge AI workflows, and grid-interactive controls) into scalable commercial products.
Core capabilities include design and manufacturing of containerized solar-battery systems; rapid field deployment logistics; energy-aware compute hosting for science and AI workloads; integration of industrial sensors and automation (PLC/CAN-based control architectures); and commercialization pathways aligned with defense, grid resilience, and research infrastructure markets. SBBI maintains strong partnerships across industry, academia, and federal programs, and is actively pursuing pathways that move technologies from TRL 4–6 validation into scalable deployments.
Through CLIMR collaboration, SBBI aims to provide a commercialization testbed that enables national labs and partners to demonstrate energy-constrained AI, resilient power systems, and deployable research infrastructure — accelerating transition from prototype to operational capability. |
| CA |
| | JarrarLabs | Nooruddin Jarrar | Founder and CEO |
Small Business
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Hydrogen and Fuel Cells
| | I build AI-powered systems that accelerate scientific discovery and obliterate commercialization barriers for deep-tech hardware.
As a PhD Candidate and the Founder/CEO of JarrarLabs, my core expertise lies in AI-driven Failure Mode and Effects Analysis (FMEA). I leverage Large Language Models (LLMs) to synthesize seemingly separate scientific disciplines, bridging reliability engineering with complex physical sciences. By using AI to rapidly form, test, and iterate physics-based hypotheses against scattered literature, I demystify complex degradation mechanisms in energy systems.
Recent breakthroughs using this workflow include:
*The SOCRATES (Solid Oxide Cell Rates) Framework: Invented a diagnostic/prognostic framework that handles simultaneous hardware failure mechanisms by combining reliability engineering with non-equilibrium statistical thermodynamics.
* Algorithmic Development: Invented a FIB-SEM multi-phase image segmentation algorithm and a Python software for automated 3D microstructural reconstruction.
* Automated Analytics: Engineered robust Python tools for the Idaho National Laboratory to automatically extract mechanistic insights from durability testing data.
At JarrarLabs, we are scaling this vision by building intelligent tools for automated testing, advanced diagnostics, and predictive control of electrochemical systems. I am passionate about applying machine learning, high-performance computing, and cross-disciplinary physics to solve the world's hardest engineering challenges. |
| CO |
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